Acute cardiac failure after sunitinib

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Acute cardiac failure after sunitinib.

Acute cardiac failure after sunitinib A 54-year-old male with cytokine-refractory metastatic renal cell carcinoma was admitted because of respiratory distress and hypotension. Five years earlier, he has been treated with alpha interferon (IFN) and interleukin-2 (two cycles of 6 weeks, s.c.) for bone, mediastinal lymph node and pulmonary metastases. Six months before admission, sunitinib (50 mg/...

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acute renal failure after cardiac surgery

acute renal failure (arf) following cardiac surgery occurs in 1 to 10% of patients. patients who develop arf have higher rates of mortality. this study was undertaken to estimate the role of perioperative variables in predicting of post cardiac surgery arf. we studied a cohort of 398 adult patients who underwent cardiac surgery at our institution from february 2004 to february 2006. adult patie...

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Acute renal failure after treatment with sunitinib in a patient with multiple myeloma

Sunitinib is a multiple tyrosine kinase receptors inhibitor that is approved for the treatment of advanced renal cell carcinoma. Amongst its targets are fetal liver tyrosine kinase receptor 3 (FLT 3) and vascular endothelial growth factor receptor (VEGFR). Renal toxicity has not been reported from the trials, but several patients have been reported to develop a pre-eclampsia-like syndrome. We r...

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[Acute renal failure after cardiac surgery under extracorporeal circulation].

Acute renal failure (ARF) following cardiac surgery under extra-corporeal circulation is a grave but infrequent complication. Numerous physiopathological factors accounting for its origin are analyzed, those related to ECC and those of the immediate post-operative period. The course of these cares of ARF and the elements of the treatment are looked at.

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Nephrotic Syndrome and Acute Renal Failure Apparently Induced by Sunitinib

We report a case of nephrotic syndrome and acute renal failure apparently induced by sunitinib. A 67-year-old man with a history of metastatic renal cell carcinoma presented with progressive kidney dysfunction with proteinuria, general edema, and body weight gain of 21 kg after undergoing 3 weeks of sunitinib therapy. The patient had taken no other over-the-counter medications, and all other po...

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ژورنال

عنوان ژورنال: Annals of Oncology

سال: 2008

ISSN: 0923-7534

DOI: 10.1093/annonc/mdn019